Endocrine Abstracts

Introduction: Medullary thyroid carcinoma (MTC) commonly metastasizes to cervical lymph nodes, liver, lungs and bone. Metastatic lesions in the breast have been previously reported but they are extremely rare and to our knowledge, this is the first case in literature described on a male patient. We report a case of a 49-year-old man with a 23-year history of sporadic MTC with bone, liver and lung metastases treated with somatostatin analogues for 6 years, who developed a painf...

Introduction: Islet hyperplasia and nesidioblastosis are described in the non neoplastic pancreas of patients with gastrinoma. It is not definately established whether hypergastrinemia can influence these changes. Moreover, rarely insulinoma and gastrinoma occur in the same patient but cases of single tumours cosecreting both insulin and gastrin have been described. Otherwise, the syndrome of hyperinsulinemic hypoglycaemia with nesidioblastosis after Roux-en-Y gastric bypass h...